Therios is for the treatment of urinary tract infections (including nephritis and cystitis) caused by organisms sensitive to cefalexin. The tablets are round scored beige palatable tablet. Each tablet contains: Cefalexin (as cefalexin monohydrate) 300 mg, 750 mg or 75 mg. The tablet can be divided into equal halves and quarters
Dogs: For the treatment of bacterial skin infections (including deep and superficial pyoderma) caused by organisms sensitive to cefalexin.
For the treatment of urinary tract infections (including nephritis and cystitis) caused by organisms sensitive to cefalexin.
15 mg cefalexin per kg bodyweight twice daily (equivalent to 30 mg per kg bodyweight per day) for duration of:
- 14 days in cases of urinary tract infection
- At least 15 days in cases of superficial infectious dermatitis
- At least 28 days in cases of deep infectious dermatitis
In severe or acute conditions the dose may be safely doubled to 30 mg/kg twice daily.
Therios tablets are well accepted by dogs, but may be crushed or added to a small quantity of food immediately prior to feeding if necessary.
Do not use in animals which are known to be hypersensitive to penicillins.
Do not use in rabbits, guinea pigs, hamsters and gerbils.
Do not use in pregnant or lactating bitches.
As with other antibiotics which are excreted mainly by the kidneys, systemic accumulation may occur when renal function is impaired. In case of known renal insufficiency the dose should be reduced.
The product is not recommended for use in dogs less than 2.5 kg bodyweight.
Safety of the excipient, ammonium glycyrrhizate, has not been established in dogs less than 1 year old.
Do not store above 25 °C. Keep out of the reach of children.
Shelf-life after first opening the blister pack: 48 hours.
Divided tablets should be stored in the blister pack. Any divided tablet portions remaining after 48 hours should be discarded.
Any unused veterinary medicinal product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
Trials performed on animals with up to 5 times the recommended dosage 15 mg/kg demonstrated that cefalexin was well tolerated.
Special precautions to be taken by the person administering the veterinary medicinal product to animals:
Cephalosporins may cause sensitization (allergy) following injection, inhalation, ingestion or skin contact. Sensitivity to penicillins may lead to cross sensitivity to cephalosporin and vice versa. Allergic reactions to these substances may occasionally be serious.
1. Do not handle this product if you know you are sensitized or if you have been advised not to work with such preparations.
2. Handle this product with great care to avoid exposure, taking all recommended precautions. Wash hands after use.
3. If you develop symptoms following exposure such as skin rash you should seek medical advice and show the doctor this warning. Swellings of the face, lips or eyes or difficulty breathing are more serious symptoms and require urgent medical attention.