Cephacare is for the treatment of infections of the respiratory tract, urogentical tract, the skin and localised infections in soft tissue caused by bacteria sensitive to cefalexin. Cephacare Flavoured Tablets are beef flavoured, beige coloured tablets with a break mark on each side and are available in 3 strengths.
Cephacare Flavoured 50mg Tablets are round biconvex tablets. Each tablet contains 50mg of cefalexin and is indicated for cats and dogs.
Cephacare Flavoured 250mg and 500mg Tablets are flat tablets. Each tablet contains 250mg and 500mg respectively and are indicated for dogs.
Cefalexin is a semi-synthetic bactericidal antibiotic belonging to the cephalosporin group which acts by
interference with bacterial cell wall formation.
Cefalexin is active against a wide range of Gram-positive and Gram-negative bacteria. The following
micro-organisms have been shown to be sensitive to cefalexin in vitro: Staphylococcus spp (including
penicillin-resistant strains), Streptococcus spp, Corynebacterium spp, Pasteurella multocida, Escherichia
coli, Micrococcus spp, Moraxella spp.
Cefalexin is resistant to the action of staphylococcal penicillinase and is therefore active against the
strains of Staphylococcus aureus that are insensitive to penicillin (or related antibiotics such as ampicillin
or amoxycillin) because of production of penicillinase.
Cefalexin is also active against the majority of ampicillin-resistant E.coli.
Indications in dogs
Treatment of infections of the respiratory tract, gastro-intestinal tract, urogenital tract, the skin and
localised infections in soft tissue caused by bacteria sensitive to cefalexin.
Indications in cats
Treatment of infections of the respiratory tract, urogenital tract, the skin and localised infections in soft
tissue caused by bacteria sensitive to cefalexin.
Dosage and administration
For oral administration. Cephacare flavour tablets have a break mark on one side. To enable more
accurate dosing, half tablets may be used as necessary. Tablets may also be added to food if
To avoid underdosing, the bodyweight should be accurately determined.
A dose of 15 mg/kg twice daily is recommended, to be doubled where appropriate.
Treatment for five days is recommended. Any increase in dose or duration of use should be according to
a risk/benefit assessment by the prescribing veterinarian (e.g. in cases of chronic pyoderma).
A dose of 15 mg/kg twice daily for 5 days is recommended.
Contra-indications, warnings, etc
For animal treatment only. Use of the product should be based on susceptibility testing and take into
account official and local antimicrobial policies.
Use of the product deviating from the instructions given in the SPC may increase the prevalence of
bacteria resistant to cefalexin and may decrease the effectiveness of treatment with penicillins, due to
the potential for cross resistance.
In the case of an allergic reaction, treatment should be withdrawn.
The administration of cefalexin has been shown to produce no serious side-effects at many times the
recommended dose rate.
As with other antibiotics which are excreted mainly by the kidneys, unnecessary accumulation may occur
in the body when renal function is impaired. In cases of known renal insufficiency the dose should be
reduced, antimicrobials known to be nephrotoxic should not be administered concurrently and the
product should be used only according to a risk/benefit assessment by the responsible veterinarian.
The safety of the product has not been demonstrated in studies in pregnant or lactating dogs and cats.
Use only in accordance with a risk/benefit assessment by the responsible veterinarian.
Transient episodes of soft faeces and vomiting have been observed in cats when given products
containing cefalexin. Treatment should be discontinued if vomiting and diarrhoea develop.
Vomiting has been observed occasionally in dogs when given products containing cefalexin.
Do not use in cases of known hypersensitivity to the active substance to other cephalosporins, to other
substances of the b-lactam group or to any of the excipients.
Do not use in rabbits, gerbils, guinea pigs and hamsters.
Penicillins and cephalosporins may cause hypersensitivity (allergy) following injection, inhalation,
ingestion or skin contact. Hypersensitivity to penicillin may lead to cross-reactions to cephalosporin and
vice versa. Allergic reactions to these substances may occasionally be serious. Do not handle this
product if you know you are sensitised or if you have been advised not to be in contact with such
substances. Handle this product with great care to avoid exposure, taking all recommended precautions.
If you develop symptoms following exposure such as skin rash you should seek medical advice and
show the doctor this warning. Swelling of the face, lips or eyes or difficulty breathing are more serious
symptoms and require urgent medical attention. In case of accidental ingestion, seek medical advice
immediately and show the package leaflet or the label to the physician.
Wash hands after use.